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When it comes to metabolizing drugs, the main enzyme family is the cytochrome P450 (CYP450). To keep this short, will CBD help me with chronic pain from numerous surgerys and facing shoulder replacement shourtly. People take CBD when they are at work, when they travel or when spending time with loved ones. So far, we’ve concluded that buying CBD creams online is a safe, secure and easy way of getting the best value for your money.